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DARPA to Develop Synthetic Biology…

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December 10, 2012 in Technology

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For those of you that doubt the agenda, you need only look at the DARPA mission statement related to the 2012 contract given to DARPA for development of synthetic biology. Continuing the technology created across biological platforms and cell types. DARPA’s Living Foundries research program for the development of biologically manufactured and “Engineered” biological systems, is part of the program. In September 2011 the agency requested monies for methodologies to transform biology into an engineering practice, expanding the complexity of biological systems that can be engineered.    o… 

Pentagon Looks to Breed Immortal ‘Synthetic Organisms,’ Molecular Kill-Switch Included… From Wired…  By Katie Drummond 02/05/10  9.42 AM

The Pentagon’s mad science arm may have come up with its most radical project yet. Darpa is looking to re-write the laws of evolution to the military’s advantage, creating “synthetic organisms” that can live forever — or can be killed with the flick of a molecular switch.

As part of its budget for the next year, Darpa is investing $6 million into a project called BioDesign, with the goal of eliminating “the randomness of natural evolutionary advancement.” The plan would assemble the latest bio-tech knowledge to come up with living, breathing creatures that are genetically engineered to “produce the intended biological effect.” Darpa wants the organisms to be fortified with molecules that bolster cell resistance to death, so that the lab-monsters can “ultimately be programmed to live indefinitely.”

Of course, Darpa’s got to prevent the super-species from being swayed to do enemy work — so they’ll encode loyalty right into DNA, by developing genetically programmed locks to create “tamper proof” cells. Plus, the synthetic organism will be traceable, using some kind of DNA manipulation, “similar to a serial number on a handgun.” And if that doesn’t work, don’t worry. In case Darpa’s plan somehow goes horribly awry, they’re also tossing in a last-resort, genetically-coded kill switch:

Develop strategies to create a synthetic organism “self-destruct” option to be implemented upon nefarious removal of organism.

The project comes as Darpa also plans to throw $20 million into a new synthetic biology program, and $7.5 million into “increasing by several decades the speed with which we sequence, analyze and functionally edit cellular genomes.”

Of course, Darpa’s up against some vexing, fundamental laws of nature — not to mention bioethics — as they embark on the lab beast program. First, they might want to rethink the idea of evolution as a random series of events, says NYU biology professor David Fitch. “Evolution by selection is nota random process at all, and is actually a hugely efficient design algorithm used extensively in computation and engineering,” he e-mails Danger Room.

Even if Darpa manages to overcome the inherent intelligence of evolutionary processes, overcoming inevitable death can be tricky. Just ask all the other research teams who’ve made stabs at it, trying everything from cell starvation to hormone treatments. Gene therapy, where artificial genes are inserted into an organism to boost cell life, are the latest and greatest in life-extension science, but they’ve only been proven to extend lifespan by 20 percent in rats.

But suppose gene therapy makes major strides, and Darpa does manage to get the evolutionary science right. They’ll also have a major ethical hurdle to jump. Synthetic biology researchers are already facing the same questions, as a 2009 summary from the Synthetic Biology Project reports:

The concern that humans might be overreaching when we create organisms that never before existed can be a safety concern, but it also returns us to disagreements about what is our proper role in the natural world (a debate largely about non-physical harms or harms to well-being).

Even expert molecular geneticists don’t know what to make of the project. Either that, or they’re scared Darpa might sic a bio-bot on them. “I would love to comment, but unfortunately Darpa has installed a kill switch in me,” one unnamed expert tells Danger Room. 

Commentary by Otter Walks…  Another source for you to pick and choose search terms, names, dates… You get the picture…  ( MAD! ) Do not forget this is money needed for many other, more practical, like, oh, I don’t know, say infrastructure!…  How about Jobs, negating the National debt, and what about all of those out dated Nuclear Reactors?… Oh, that’s right they are dumping that and all of their medical and petrochemical waste out of the skies on US!  I guess it does not matter when you have an executive that, in this day, sets off Atom Bombs, in Nevada? You did hear about that, yes?  Meanwhile back in the land of the sane, that is what is left of it, we have these people (?) not only making, but testing this on us!   Survive-All…     o…   10/12/12



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1 response to DARPA to Develop Synthetic Biology…

  1. Absoultly, The Pentagon’s mad science arm may have come up with its most radical project yet. http://www.vpillssatis.gen.tr/v-pills-izmir.html

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